Matthias Kroiss Selected Research

Mitotane (Lysodren)

2/2020	Effects of Germline CYP2W16 and CYP2B66 Single Nucleotide Polymorphisms on Mitotane Treatment in Adrenocortical Carcinoma: A Multicenter ENSAT Study.
1/2020	Expression of SOAT1 in Adrenocortical Carcinoma and Response to Mitotane Monotherapy: An ENSAT Multicenter Study.
1/2020	A Micellar Mitotane Formulation with High Drug-Loading and Solubility: Physico-Chemical Characterization and Cytotoxicity Studies in 2D and 3D In Vitro Tumor Models.
1/2020	Next-generation therapies for adrenocortical carcinoma.
1/2020	Objective Response and Prolonged Disease Control of Advanced Adrenocortical Carcinoma with Cabozantinib.
10/2019	Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis.
7/2019	A method for the minimally invasive drug monitoring of mitotane by means of volumetric absorptive microsampling for a home-based therapeutic drug monitoring.
2/2019	Advanced Adrenocortical Carcinoma - What to do when First-Line Therapy Fails?
1/2019	Hsp90 inhibition in adrenocortical carcinoma: Limited drug synergism with mitotane.
1/2018	Mitotane Monotherapy in Patients With Advanced Adrenocortical Carcinoma.

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Matthias Kroiss Research Topics

Disease

39	Neoplasms (Cancer) 01/2022 - 01/2011
37	Adrenocortical Carcinoma 01/2022 - 02/2010
10	Cushing Syndrome 01/2022 - 06/2011
7	Paraganglioma (Paragangliomas) 01/2022 - 01/2019
7	Thyroid Neoplasms (Thyroid Cancer) 10/2021 - 01/2018
6	Pheochromocytoma 01/2022 - 01/2019
4	Adenoma (Adenomas) 01/2022 - 08/2015
4	medullary Thyroid cancer 11/2021 - 01/2019
4	Adrenocortical Adenoma (Disease, Conn's) 04/2021 - 08/2017
3	Hyperplasia 05/2022 - 01/2017
3	Hypertension (High Blood Pressure) 01/2022 - 04/2014
3	Neoplasm Metastasis (Metastasis) 06/2021 - 08/2017
3	Disease Progression 10/2019 - 06/2012
2	Adrenal incidentaloma 01/2022 - 01/2021
2	Lymphatic Metastasis 01/2021 - 02/2019
2	Obesity 12/2020 - 12/2006
2	Hyponatremia 01/2020 - 08/2018
2	Carcinoma (Carcinomatosis) 01/2020 - 08/2015
2	Fatigue 10/2019 - 04/2015
2	Rare Diseases (Rare Disease) 12/2018 - 12/2016
1	Hypoparathyroidism 01/2022
1	7 Hereditary Prostate Cancer 01/2022
1	Vocal Cord Paralysis 01/2022
1	Prostatic Neoplasms (Prostate Cancer) 01/2022
1	Inborn Errors Steroid Metabolism 11/2021
1	Thyroid Diseases (Thyroid Disease) 11/2021
1	Thyroid Nodule (Nodule, Thyroid) 11/2021
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 11/2021
1	Hypophysitis 11/2021
1	Thromboembolism 10/2021
1	Acute Coronary Syndrome 10/2021
1	Hemorrhage 10/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 10/2021
1	Parathyroid Neoplasms (Parathyroid Neoplasm) 08/2021

Drug/Important Bio-Agent (IBA)

20	Mitotane (Lysodren)FDA Link 02/2020 - 02/2010
11	Pharmaceutical PreparationsIBA 01/2022 - 11/2011
8	Hydrocortisone (Cortisol)FDA LinkGeneric 05/2022 - 04/2014
7	SteroidsIBA 11/2021 - 06/2011
6	Hormones (Hormone)IBA 01/2022 - 06/2011
5	cabozantinibIBA 01/2022 - 01/2020
5	Tyrosine Kinase InhibitorsIBA 10/2021 - 01/2011
4	Biomarkers (Surrogate Marker)IBA 11/2021 - 10/2019
4	vandetanib (ZD6474)IBA 01/2021 - 01/2018
4	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020 - 02/2010
4	Cisplatin (Platino)FDA LinkGeneric 01/2020 - 02/2010
4	Etoposide (VP 16)FDA LinkGeneric 01/2020 - 02/2010
3	CatecholaminesIBA 01/2022 - 12/2019
3	Phosphotransferases (Kinase)IBA 01/2022 - 06/2021
3	SterolsIBA 01/2022 - 11/2015
3	Sunitinib (Sutent)FDA Link 01/2022 - 01/2011
3	TransferasesIBA 01/2022 - 11/2015
3	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 12/2019
3	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 01/2017
3	lenvatinibIBA 10/2021 - 01/2021
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 10/2008
3	LipidsIBA 01/2019 - 11/2015
2	Gemcitabine FDA Link 01/2022 - 11/2017
2	EnzymesIBA 01/2022 - 11/2021
2	selpercatinibIBA 01/2022 - 01/2020
2	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2022 - 01/2021
2	Immune Checkpoint InhibitorsIBA 11/2021 - 01/2021
2	Sorafenib (BAY 43-9006)FDA Link 10/2021 - 01/2020
2	pembrolizumabIBA 01/2021 - 01/2021
2	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2021 - 01/2021
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2021 - 12/2020
2	prolinedithiocarbamate (PDTC)IBA 01/2021 - 01/2021
2	CateninsIBA 01/2021 - 06/2011
2	GlucocorticoidsIBA 01/2020 - 11/2011
2	PolyaminesIBA 01/2020 - 08/2017
2	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2020 - 01/2019
2	Chemokine ReceptorsIBA 01/2020 - 01/2017
2	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2019 - 01/2018
2	Streptozocin (Streptozotocin)FDA Link 06/2012 - 02/2010
1	Cholesterol Esters (Cholesteryl Esters)IBA 01/2022
1	CholesterolIBA 01/2022
1	Everolimus FDA Link 01/2022
1	N- (4- methoxybenzyl)- N'- (5- nitro- 1,3- thiazol- 2- yl)ureaIBA 01/2022
1	AlpelisibIBA 01/2022
1	trametinibIBA 01/2022
1	Mixed Function Oxygenases (Monooxygenases)IBA 01/2022
1	entinostat (MS 275)IBA 01/2022
1	niraparibIBA 01/2022
1	Zoledronic Acid (Zometa)FDA Link 01/2022
1	Sulfates (Sulfates, Inorganic)IBA 11/2021
1	Estrogens (Estrogen)FDA Link 11/2021
1	IodineIBA 11/2021
1	Calcitonin (Calcitonin, Eel)FDA LinkGeneric 11/2021
1	cyclopropapyrroloindoleIBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	pazopanib FDA Link 10/2021
1	PlatinumIBA 10/2021
1	Parathyroid Hormone (Parathormone)IBA 08/2021

Therapy/Procedure

16	Therapeutics 01/2022 - 02/2010
7	Drug Therapy (Chemotherapy) 10/2021 - 04/2015
3	Immunotherapy 05/2021 - 01/2020
2	Renal Dialysis (Hemodialysis) 10/2021 - 06/2014
2	Precision Medicine 12/2018 - 01/2017
2	Salvage Therapy 01/2016 - 02/2010
1	Parathyroidectomy 01/2022
1	Lasers (Laser) 11/2021